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Molecular Motors Move You

first_imgThe realization that cells are filled with molecules that move like machines fascinates many people.  Students who grew up thinking of chemistry as bouncing molecules that did little more than link up and separate have a whole new paradigm to consider: molecules that walk, fold and unfold, spin and operate like ratchets, robots, wrenches and motors.  Here are a few recent developments in the world of molecular machines:Brownian walk:  Researchers in Science1 reported that myosin, a molecular “walking” motor used in muscle, harnesses the random force of Brownian motion to keep on track.  Brownian motion is the random shuddering action of small molecules due to thermal motion in the environment.  Like sails in the wind, myosin motors are built in such a way that they can make use of the vector component corresponding to the direction they need to go.  “The leading neck swings unidirectionally forward, whereas the trailing neck, once lifted, undergoes extensive Brownian rotation in all directions before landing on a site ahead of the leading head,” said Shiroguchi and Kinosita.  “The neck-neck joint is essentially free, and the neck motion supports a mechanism where the active swing of the leading neck biases the random motion of the lifted head to let it eventually land on a forward site.”  This way they get a push for free.  The authors did not discuss how this mechanism might have evolved.Gut-level machinery:  Speaking of myosin, did you know it aids digestion?  Your digestive tract is lined with microvilli, tiny projections that vastly increase the surface area of the intestinal membrane that absorbs nutrients.  Now, scientists have found there’s a lot more going on in the tips of these projections.  Science Daily reported on work at Vanderbilt that showed myosin is concentrated in the tips and appears actively involved in shedding membrane material at the tips.  This process of vesicle formation and detachment may inject metabolic enzymes into the passing food material, as well as protect the lining of the intestine from invaders.  It’s all done with motors: myosin 1a, “a protein with the potential to generate force and move cargo around in cells.”  Matthew Tyska figured that there must be a reason these force-generating motors are concentrated in the microvilli, and sure enough, he found them at work: “It’s a little machine that can shed membrane from the tips,” he said.  This could give a whole new dimension to the term bowel movement.  Now his group is seeing if a similar mechanism operates in other cellular projections, like the hair cells of the inner ear.  See also EurekAlert.Clockworks:  A paper in Nature discussed the latest research into the molecular mechanisms behind biological clocks.2  There is not one clock molecule involved, but a host of proteins that form feedback loops in cycles that express and repress certain genes in response to environmental cues.  One of the proteins is even nicknamed CLOCK.  The article payed particular attention to PGC-1-alpha, a protein that appears intimately linked to both the circadian rhythm and metabolism, affecting the production of glucose, fatty acids and haem (iron-containing molecules).  Many questions remain, however.  This is clearly a work in progress.Splice and dice:  Another paper in Nature used the word “machinery” six times, speaking of the spliceosome.3  “A complex macromolecular machinery in the nucleus of eukaryotic cells is responsible for pre-mRNA splicing,” said Blencowe and Khanna.  They described how alternative splicing “is a remarkably efficient mechanism for a cell to increase the structural and functional diversity of its proteins, and it plays many roles in gene regulation” (see 05/20/2007).  The way alternative splicing is controlled is by RNA “riboswitches,” including messenger-RNA transcripts that can regulate their own expression with feedback and feed-forward loops.  These riboswitches can actually change shape in response to cues, and the shape determines how the gene will be expressed.  The authors used the word switch 18 times.    Earlier, riboswitches were thought to exist only in bacteria and fungi, but now it appears they may be common in higher animals and in plants.  The authors speculated about evolution’s place in this: “It seems plausible that splicing-regulatory riboswitches represent a system that has evolved to coordinately regulate multiple genes in the same biochemical pathway using feedback and, in some cases, feed-forward mechanisms,” they asserted.  “Presumably, the rapid kinetics and energy-saving advantages afforded by bypassing protein-mediated regulation explain why riboswitch aptamers have persisted during evolution and function at many levels of regulation of gene expression.”  Yet this seems to assume what needs to be proved.  They used the presence of these switches, and the advantages they appear to confer, as evidence they evolved, yet provided no details on how that could have occurred by natural selection.  By contrast, the evidence they did provide shows the opposite of evolution: between very distant organisms, like fungi and higher plants, the genes involved are “evolutionarily conserved” (i.e., unevolved).Machine language:  Two scientists publishing in PNAS sounded like factory planners, but were talking about cells.4  “Experimental and theoretical studies of proteins, acting as motors, ion pumps, or channels, and enzymes, show that their operation involves functional conformational motions,” they said.  A few sentences later, the machine talk continued: “Generally, a machine is a mechanical device that performs ordered internal motions that are robust against external perturbations.”  They were discussing how molecular machines in the cell, particularly myosin and ATP synthase, are examples of such robustness.  “In conclusion,” they said in the final discussion section, “we have shown that motor proteins possess unique dynamical properties, intrinsically related to their functioning as machines.”  This recalls a line Scott Minnich said in the film Unlocking the Mystery of Life: “It’s not convenient that we give them these [machine] names; it’s truly their function.”    Part of the title read, “design principles of molecular machines.”  Yet the authors attributed this design to undirected chance processes of evolution in this statement: “Actual proteins with specific architectures allowing robust machine operation may have developed through a natural biological evolution, with the selection favoring such special dynamical properties.”  They ran a simulation of an “evolutionary computer optimization process” and achieved a “artificial elastic network architectures possessing machine-like properties,” but this statement blurs the line between intelligently-selected outcomes and chance.“Machine” language is quite common in the scientific literature.  One often finds matter-of-fact discussion of proteins and enzymes as machines.  They use energy and perform physical work according to tight specifications.  The evolutionary conundrum is: how could functioning machines arise from non-functional matter in motion?  Authors of scientific papers typically either ignore the question, or assume evolution did the design work.    A more fruitful approach was offered by a biophysicist who wrote Nature last week, suggesting that we “Look at biological systems through an engineer’s eye.”5  R. S. Eisenberg said that when approaching a black box, whether an amplifier in a sound system or an unknown mechanism in a living cell, we should identify the inputs and outputs, the power supply and the device equation.  Looking at biological devices with the eyes of an engineer, he said, can lead to fruitful experiments:Complex systems – for example, with many internal nonlinear connections like the integrated circuit modules of digital computers or, perhaps, the central nervous system – may not be easily analysed as devices, no matter how many experimental data are available.  But it seems clear, at least to a physiologist, that productive research is catalysed by assuming that most biological systems are devices.  Thinking today of your biological preparation as a device tells you what experiments to do tomorrow.    Asking the questions in this way leads to the design of useful experiments that may eventually lead to the device description or equation, if it exists.  If no device description emerges after extensive investigation of a biological system, one can look for other, more subtle descriptions of nature’s machines.An intelligent design scientist might feel vindicated.  No evolutionary theorizing is needed in this approach.  Assuming design in the device, and asking engineering questions, can stimulate a fruitful experimental program.1Shiroguchi and Kinosita, “Myosin V Walks by Lever Action and Brownian Motion,” Science, 25 May 2007: Vol. 316. no. 5828, pp. 1208-1212, DOI: 10.1126/science.1140468.2Grimaldi and Sassone-Corsi, “Circadian rhythms: Metabolic clockwork,” Nature 447, 386-387 (24 May 2007) | doi:10.1038/447386a.3Blencowe and Khanna, “Molecular biology: RNA in control,” Nature 47, 391-393 (24 May 2007) | doi:10.1038/447391a.4Togashi and Mikhailov, “Nonlinear relaxation dynamics in elastic networks and design principles of molecular machines,” Proceedings of the National Academy of Sciences USA, 10.1073/pnas.0702950104, published online before print May 16, 2007.5R. S. Eisenberg, “Look at biological systems through an engineer’s eye,” Correspondence, Nature 447, 376 (24 May 2007) | doi:10.1038/447376a.These papers speak for themselves.  Was anybody impressed by the evolutionary storytelling?  Was it useful?  Did it contribute to understanding in any way?  How about, on the other hand, the machine language?  Can you talk machine language without assuming intelligent design?  Where do you think science is headed?  Bye-bye, Charlie.(Visited 6 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

SA’s Angoras give diabetics relief

first_imgMohair-producing Angora goats were brought to South Africa from Turkey over 150 years ago.(Image: Rodger Bosch,MediaClubSouthAfrica.com. For more freephotos, visit the image library.) The natural elasticity of mohair stimulates blood circulation while its high absorption rate draws moisture away from the foot.(Image: Cape Mohair)MEDIA CONTACTS • Cape Mohair Neil McCleland neilm@capemohair.com Denys Hobson +27 21 534 4134 • Mohair South Africa +27 41 48 71386 RELATED ARTICLES • 2009 – The Year of Natural Fibres • Natural fibre takes off • Climate change and camels • Growing the organic business • Botswana revives ostrich farmingWilma den HartighSouth Africa is the world’s leading producer of mohair, a unique natural fibre produced by Angora goats. Now the fibre’s special properties are helping diabetics across the world avoid one of the disease’s most debilitating effects.One of the complications of diabetes, a disease suffered by some 300-million people across the world, is a reduction of blood circulation to the extremities. This causes foot problems such as infections and ulcers and, in extreme cases, can lead to amputation. For diabetics, foot care is crucial.A new range of socks developed by South African mohair processor Cape Mohair offers better foot protection to diabetics worldwide. Called the Medi Sock, it makes us of mohair’s natural elasticity that enhances circulation, and high absorption rate that draws moisture away from the foot.“These are the fantastic attributes of mohair that people don’t always know about,” said Denys Hobson, chief executive of Cape Mohair.Cape Mohair examined similar products sold elsewhere in the world, but none of them were adequate. “We realised that there is a great need for decent socks for diabetics,” Hobson said. Before the product was launched, it was tested for eight months and refined many times over with the help of people living with diabetes.The socks are made from locally produced mohair yarn from Angora goat kids, which provide a fine-textured hair. Coarser mohair will irritate the foot.Neil McCleland of Cape Mohair said the export potential of the sock could lead to the consumption of an additional 30 tons of mohair a year. This will be a significant boost for South Africa’s mohair industry, already considered the world’s leading producer of the natural fibre.The Medi Sock is fast gaining market share and recognition internationally; in the UK it is already considered a product leader. Cape Mohair recently received its 21st bulk export order from the UK, and plans to expand the sock’s market into the US and Europe.South Africa’s mohair industrySo far, conventional uses of mohair have been in the fashion industry, interior design and by craft and industrial fibre specialists. Rugs, blankets, throws and shawls are some of the more well-known mohair products.According to Hobson, South Africa’s well-established mohair industry produces over 60% of the world’s mohair. Some 95% of the fibre is exported to countries such as Italy, China, the UK and France.Production is concentrated in the Eastern Cape province, considered to be the mohair capital of the world: 80% of all South African mohair production comes from the region. The country has two of the world’s major combing mills, where the “greasy” fibre is processed to combed mohair tops. Mohair yarn is manufactured in Port Elizabeth and Uitenhage, in the Eastern Cape.Finished products such as rugs and blankets are also produced in the province, and mostly exported. Interestingly, South Africa is not a large end user of mohair, as the fibre has never been marketed locally.Farming Angoras for 150 yearsAngora goats were introduced to South Africa in the 19th century, but only by lucky chance.According to Mohair South Africa, the goat is believed to originate from the mountains of Tibet, making its way to Turkey in the 16th century.The story goes that in the 1800s a South African farmer in Turkey wanted to establish the breed in his own country. But the Turkish sultan he approached, who knew the value of the goats, was not keen to share his secret. So in 1838 the sultan sent the breeder 12 infertile Angora rams and a single ewe. But unknown to him, the ewe was pregnant, and gave birth to a ram kid. This was the beginning of Angora breeding in South Africa.Over the past 150 years attentive stock management has made the South African Angora goat the dominant producer of fine mohair fleece in the world. Selective breeding has also made the local variety hardier, able to thrive in South Africa’s harsh dry conditions“Good breeding has always been a priority in the sector and farmers have done this to ensure the quality of the wool remains high,” said Hobson. “Farmers’ attention to detail has contributed to sector being held in such high esteem internationally.”In the past two decades world mohair production has dropped considerably, from a peak of 26-million kilograms in 1988 to 5.3-million kg in 2008. Reasons for the decline include the labour-intensive nature of mohair farming, price sensitivity due to fashion trends, and the conversion of South African Angora goat farmland to game ranching.The introduction of game farming in the Eastern Cape has had a negative impact on Angora goat farming in the region, Hobson said. However, some farmers have re-established their operations in the western parts of South Africa. The goats seem to thrive in the region, so much so that in some cases they are replacing the area’s traditional ostrich farming.International Mohair SummitIn celebration of the International Year of Natural Fibres, South Africa will be hosting the inaugural international biennial Mohair Summit from 3 to 8 November in Jansenville and Graaff-Reinet in the Karoo. The event will be attended by local and international growers, buyers, manufacturers, sellers, fashion designers and interior decorators.The United Nations declared 2009 the International Year of Natural Fibres in an attempt to highlight the role that natural fibres play in contributing to food security and poverty alleviation.The use of natural fibres in clothing, household furnishings and industries has declined as a result of the development of synthetic fibres. Synthetic materials such as polyester, acrylic and nylon are widely used because they are cost effective and can be mass-produced. Sadly, competition from synthetic materials has affected millions of people who rely of the production and processing of natural fibre for their income.last_img read more

Useful black comb head band, Love it, have ordered a few more

first_imgGood good quality & extremely reasonable rate. Exactly what my daughter desired, very good high-quality & extremely affordable cost, prompt shipping and delivery also.It’s a bit also significant, but even now a little something i use to continue to keep my hair back all over the residence when i am cleansing.Great solution retains hair back and of encounter.Key specs for Useful black comb head band. Holds hair back firmly and stays in place. Great hair accessory for everyday wear.:Black Shark Tooth DesignHandy for Keeping Hair from Your FaceComments from buyers“Ban frizzy hair with this band, Now it is perfect and I wear it a lot, good; ive not broken this one yet!, for my grandaughter, Comfortable pretty headband, Love it, have ordered a few more”This headband is a superior solution whilst i discovered it was as well massive for my head as in there was an excessive band possibly facet of my head – even though if you have extremely thick hair it would possibly be just suitable .I loved sporting it but sadly it snapped just after a number of wears :(would purchase one more just one nevertheless as they are affordable enough.Great company, good merchandise. I recognize their services as it arrived at the time i desired, the products is good and it holds the hair properly well. The only issue that i disliked is that it breaks very conveniently. Usually, seriously great item.I failed to expect this to be so at ease or useful. I have extremely prolonged hair and it is just suitable to prevent it flopping in my eyes through gardening and housework. Headbands slither off my head and i seem a pig with it tied back so this is fantastic.Excellent head band to retain hair away from drinking water as you wash.Holds hair firmly and stays in spot i’m really content with my. Indeed it holds hair firmly and stays in placei’m very pleased with my acquire.When this arrived, i believed it seemed low-priced and plasticy and would not be any good. . Even so when i tried using it, i was surprised and very joyful with it 🙂 it seems to be really pretty it my hair, which is really prolonged and thick, and it stays in area 🙂 lovely item.Virtually the up coming working day shipping and delivery, excellent assistance. The band alone is outstanding, it matches my head without the need of hurting, there is no pressure on the scalp and holds my hair back completely – hugely recommended.This item is good, it arrived quite swiftly and i am moderately. This product is high-quality, it arrived quite swiftly and i am fairly happy with it. There is certainly nothing at all improper with the merchandise but it is not totally suitable for my extremely thick hair.Great sturdy hairband that does what it is really intended to – maintain the hair back firmly. First rate dimensions so is cozy. I have genuinely thick hair and it copes with the bulk of my hair well.This basically does preserve ypur hair in place.Ban frizzy hair with this band. I have pretty curly and from time to time frizzy hair and i am not generally in the temper to straighten my hair every day. Sometimes i just fancy leaving it to dry obviously and experience the repercussions. Now i can use this band to tame my mane. It holds the hair in place and doesn’t itch or put stress on the scalp. It will not move all around and is simple to place in and choose out.Purchased this two times ago and arrived early then predicted day matches nicely genuinely happy.This merchandise is okay- nothing mistaken with it. On the other hand i did stop up purchasing another from boots in the close as i wanted a person with much more grip- as this 1 felt a little bit loose.Really speedy shipping, excellently packaged. The hair baind is extremely massive. Eithe i will not have adequate hair, or a major sufficient head for it , so it isn’t going to stay in place.No problems its great for the selling price. No issues its great for the rate.Looks accurately as in the photograph and does its occupation flawlessly. It hold my hair firmly but without hurting.Love it, have requested a several additional. This is great, i acquired it just to have on all around the house to keep hair out of my eyes but it truly tends to make your hair seem great so i have ordered a few a lot more so i have a source. In contrast to other head bands i have bought it just isn’t far too limited and is really snug to wear.Quite amazed with this for the selling price – both equally i and my ten yo daughter use it and it has proved up to the position so much.Obtaining broken her past headband we have searched in all places for one like it. She enjoys this as it holds her hair in spot and doesn t go.Now it is ideal and i wear it a great deal. This is the most straightforward to wear of the headbands i have – as opposed to the elastic type it will never work its way lackwards off your head, and as opposed to the steel form it is not scratchy and lies flush in opposition to the scap so not obtrusive. A person adaptation i built to it even though to get it specifically the ideal suit for me as i am incredibly fussy, is the reduce off the lowest half of the ‘arms’ as i found they dug in a minimal when i was resting in the motor vehicle or airplane on my facet. Now it is great and i wear it a good deal.last_img read more

Rajasthan doctors call off stir as govt. accepts demands

first_imgThe agitating doctors of government hospitals in Rajasthan have called off their 11-day-long strike following an agreement with the State government that has addressed their concerns. Over 80 doctors were arrested during the strike when the Essential Services Maintenance Act was invoked.The strike ended late on Wednesday night, just two days after the Rajasthan High Court directed the government to proceed “in accordance with law” to bring the in-service doctors back to work. Medical and Health Minister Kali Charan Saraf said there were “some misunderstandings” that had been resolved through the agreement.The government has accepted the doctors’ demand for appointment of a medical expert to the post of Additional Director (Gazetted) in the Directorate of Health Services by replacing an Administrative Officer. On the demand for revocation of transfer of 12 doctors after the earlier strike last month, the government has agreed to post them at places convenient for them.The doctors had gone on mass leave, demanding implementation of an agreement on the issues of dynamic accelerated career promotion, increasing rural allowances of doctors, among others.last_img read more

ESPN The Magazine Launches Own Web Site

first_imgAfter 10 years in print, ESPN The Magazine is finally getting its own Web site. Today, the company launched ESPNthemag.com, the first site dedicated exclusively to the magazine.“It was time,” says Robbyn Footlick, executive editor of multimedia. “A big ESPN initiative right now is focusing on developing all its content across all its platforms, so now seemed the right time to build out the magazine’s content online, including video.”The new site has been programmed like a TV network, Footlick explains, with a focus on what she calls “lunchtime programming” and updates throughout the day through blogs (what appears to be ESPN’s most aggressive blogging initiative to date) and a news infographic called “The World According to Us.” The site also features magazine content, online-exclusive stories and video. As part of the magazine’s 10th anniversary, the site includes a separate anniversary channel, featuring an interactive gallery of the more than 270 covers since the magazine’s launch.“The magazine has a different feel than the rest of the ESPN site and we really needed to represent that,” says Gabe Garner, director of interactivity for Sarkissian Mason, the firm that developed the site. He says the process took about six months. “We took a ground-up approach to the design and architecture of the site. We first needed to find ways regular readers of the magazine could get the print content they’re used to online. Then, we began to add rich media flourishes like ‘The World According to Us.’ That became a real centerpiece for bringing the magazine’s unique voice to the Web.”The site was soft-launched on Friday.last_img read more

Shawsheen Tech Students Earn 70 Medals At SkillsUSA Competition with PHOTOS

first_imgBILLERICA, MA — On Thursday, March 14, 2019  Shawsheen Tech sent 189 students to compete at the SkillsUSA District Competition at Greater Lowell Regional Technical High School. The students competed against schools in their technical areas, challenging their knowledge, in hopes of qualifying for State Competition held this April. Shawsheen students took a written assessment in their technical/trade, an additional test for employability and SkillsUSA Knowledge, as well as an OSHA test in safety. At the end of the day, Shawsheen brought home a total of 70 medals. Gold Medal Winners:Brooke MacInnes, Grade 12, Billerica, Architectural DraftingAmaan Shaikh, Grade 12, Billerica, Automated Manual Technician – DrafterCorrina Jarzynka, Grade 12, Billerica, Culinary ArtsElaina Cobb, Grade 12, Billerica, Health Knowledge BowlSkylar McGarry, Grade 12, Billerica, Medical AssistingCaitlyn Tsoukalas, Grade 12, Billerica, Medical MathFancis O’Connor, Grade  10, Billerica, Power Equipment TechnicianMohammadali Khalifa, Grade 10, Billerica, Robotics & Automation TechnicianJoshua Cabral, Grade 11, Billerica, Team Works – ElectricianTroy Tamis, Grade 12, Billerica, Team Works – PlumberGrace Clark, Grade 11, Bedford, State Officer CandidateAshley Pergamo, Grade 12, Burlington, Automotive Refinishing TechnologyCameron Hudson, Grade 12, Burlington, MechatronicsThomas Vincent, Grade  12, Burlington, Mobile Robotic TechnologyJasin Hensley, Grade 10, Burlington, Robotics & Automation TechnicianMadison Shipka, Grade 12, Burlington, Urban Search & RescueJason Elias, Grade 11, Tewksbury, Automated Manual Technician -MachinistKevin Realejo, Grade 11, Tewksbury, Automated Manual Technician -MachinistJodi Bagrowski, Grade 11, Tewksbury, EstheticsSarah Molander, Grade 11, Tewksbury, Graphic CommunicationsLeah Veloz, Grade 11, Tewksbury, Health Knowledge BowlAllyson Haley, Grade 11, Tewksbury, Health Knowledge BowlMichael Reppucci, Grade 12, Tewksbury, Industrial Motor ControlBrooke Gerry, Grade 11, Tewksbury, MasonryJohn Nowell IV, Grade 12, Tewksbury, MechatronicsDylan Melanson, Grade 12, Tewksbury, PlumbingZachary Kelly, Grade 11, Tewksbury, Team Works – CarpenterJames MacKenzie, Grade 12, Tewksbury, Team Works – MasonAnnalea Martins, Grade  11, Wilmington, Basic Health Care SkillsZachary Dancewicz, Grade 12, Wilmington, CarpentryNathan Helmar, Grade 12, Wilmington, Diesel Equipment TechnicianJuila Messina, Grade 11, Wilmington, Graphic Imaging SublimationOlivia Sanchez, Grade 10, Wilmington, Health Knowledge BowlAndrew Miller, Grade 12, Wilmington, Mobile Robotic TechnologyCelina Barczak, Grade 11, Wilmington, Nursing AssistingAmanda Howell, Grade 10, Wilmington, Technical DraftingJames Ward, Grade 12, Wilmington, Urban Search & RescueSilver Medals Winners:Connor Rich, Grade 11, Billerica, Architectural DraftingEmily Morris, Grade 12, Billerica, Dental AssistantDaniel Matarazzo, Grade 12, Billerica, Diesel Equipment TechnicianCassidy Bulmer, Grade 12, Billerica, Health Knowledge BowlBrayden Taylor, Grade 11, Billerica, Mobile Robotic TechnologyMatthew Canadas, Grade 11, Billerica, Mobile Robotic TechnologyMackenzie Cassidy, Grade 12, Billerica, Nursing AssistingShaunna Ford, Grade 12, Billerica, Screen Print TechnologyTaylor Sacco, Grade 11, Bedford, Health Knowledge BowlAntavious Nordquist, Grade 10, Bedford, Technical DraftingChristina Paras, Grade 11, Burlington, Graphic Imaging SublimationJenna Hensley, Grade 11, Burlington, Health Knowledge BowlJames Sweeney, Grade 11, Burlington, PlumbingAnthony Prezioso, Grade 10, Tewksbury, CarpentryRachel Conway, Grade 12, Tewksbury, MasonryMichael Rosa, Grade 11, Tewksbury, Team Works – CarpenterDavid Williams III, Grade 11, Tewksbury, Team Works – ElectricianBrendan Gray, Grade 11, Tewksbury, Team Works – T2 PlumberCole Privetera, Grade 11, Tewksbury, Health Knowledge BowlMadison Musto, Grade 12, Wilmington, Team Works – MasonJessica Stevens, Grade 11, Wilmington, Technical Computer ApplicationsBronze Medal Winners:Taylor Thurell, Grade 12, Billerica, Basic Health Care SkillsZachary Langlois, Grade 11, Billerica, CarpentrySamantha Collins, Grade 12, Billerica, Health Knowledge BowlBrooke Amato, Grade 12, Billerica, Health Knowledge BowlShawn Powderly, Grade 12, Billerica, PlumbingMichael Cremens, Grade 11, Billerica, Sheet MetalVeronika Bazzinotti, Grade 12, Tewksbury, Dental AssistantCameron Loder, Grade 10, Tewksbury, Diesel Equipment TechnicianAlexa Krogstie, Grade 11, Tewksbury, Health Knowledge BowlMadison Gray, Grade 12, Tewksbury, Health Knowledge BowlTaryn King, Grade 12, Wilmington, Graphic CommunicationsAmanda Ramsdell, Grade 11, Wilmington, MasonryGold and silver medal winners have earned their ticket to the annual State Leadership & Skills Conference.At that Conference, more than 2,500 students will compete in 86 occupational and leadership skill areas. Shawsheen students will compete in the practical skills portion of each contest to become a Gold medalist from Massachusetts, earning the opportunity to join more than 6,000 students to compete in the annual national-level SkillsUSA Championships.Photos:Sweeping in Carpentry: Tewksbury sophomore Anthony Preziso (silver), Wilmington senior Zachary Dancewicz (gold), & Billerica junior Zachary Langlois (bronze)Winning the gold medal in culinary arts was Billerica senior Corrina JarzynkaTaking gold in the Health Knowledge Bowl were Tewksbury junior Leah Veloz, Wilmington sophomore Olivia Sanchez, Billerica senior Elaina Cobb, and Tewksbury junior Allyson Haley. Elaina and Leah are hoping to lead another team to nationals this year.Sweeping the Masonry contest: Tewksbury senior Rachel Conway (silver), Tewksbury junior Brooke Gerry (gold), & Wilmington junior Amanda Ramsdell (bronze)Sweeping in the Plumbing contest: Burlington junior James Sweeney (silver), Tewksbury senior Dylan Melanson (gold), and Billerica senior Shawn Powderly (bronze)Winning the silver medals in screening was Billerica senior Shaunna Ford. Shaunna is hoping for another chance to attend the National Conference and better her 4th place standing in the nation.Winning gold in Team Works: Back — Tewksbury senior James MacKenzie, Left to Right: Tewksbury junior Zachary Kelley, Billerica senior Troy Tamis, & Billerica junior Joshua CabralBring home medals in Technical Drafting were Wilmington sophomore Amanda Howell (gold) and Bedford sophomore Antavious Nordquist (silver)(NOTE: The above press release is from the Shawsheen Tech.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedShawsheen Tech Students Win 30 Medals At SkillsUSA State ConferenceIn “Education”Shawsheen Tech Celebrates SkillsUSA National MedalistsIn “Education”4 Wilmington Students Earn SkillsUSA Medals At Shawsheen TechIn “Education”last_img read more

Elon Musk says Mars and Starship update could come later this month

first_img Best Buy Preview • iPhone XS is the new $1,000 iPhone X Apple AirPods with Wireless Charging Case: $155 (save $45) DJI Osmo Action camera: $261 (save $89) Turo Elon Musk shows off the shiny SpaceX Starship $999 See at Amazon See It Rylo Apple iPhone XS Mentioned Above Apple iPhone XS (64GB, space gray) JBL Soundgear wearable speaker: $90 (save $160) 1 The Cheapskate Read DJI Osmo Action preview Rylo 5.8K 360 Video Camera: $250 (save $250) See at Turo Comment Lenovo Smart Clock: $59.99 (save $20) TVs Speakers Mobile Accessories Cameras Laptops Automobiles Smart Speakers & Displays The business end of the SpaceX Starship hopper prototype Elon Musk/SpaceX Less than three years after dazzling the world with a slideshow about going to Mars, SpaceX founder and real-life comic book character Elon Musk aims to present a progress report. But we’ll have to wait until after his red planet rocket gets off the ground for the first time.Musk said Sunday on Twitter that he “will do Starship presentation a few weeks after Hopper hovers, so prob late July.” Turo: Save $30 on any car rental Read the Rylo camera preview 7 Spotify and most other streaming services rely on compressed audio, which robs the listener of full fidelity. Enter Tidal, the only “major” service that delivers lossless audio — meaning at least on par with CD quality, if not better. Want to see (er, hear) the difference for yourself? Grab this excellent extended trial while you can. It’s just $6 for three months, and it’s good for up to six listeners. What’s cooler: A snapshot of a firework exploding in front of you, or full 360-degree video of all the fireworks and all the reactions to seeing them? Oooh, ahhh, indeed. At $250, the compact Rylo dual-lens camera is selling for its lowest price yet. And for an extra $50, you can get the bundle that includes the waterproof housing.This deal runs through Sept. 3; it usually costs $500. CNET may get a commission from retail offers. $999 Google Nest Hub: $59 (save $70) $90 at Daily Steals via Google Express Sarah Tew/CNET I thought this might be a mistake, but, no, the weirdly named HP Laptop 15t Value is indeed quite the value at this price. Specs include an Intel Core i7 processor, 12GB of RAM, a 256GB solid-state drive and a 15.6-inch display. However, I strongly recommend paying an extra $50 to upgrade that display to FHD (1,920×1,080), because you’re not likely to be happy with the native 1,366×768 resolution. Formerly known as the Google Home Hub, Google’s Nest Hub packs a wealth of Google Assistant goodness into a 7-inch screen. At $59, this is within a buck of the best price we’ve seen. It lists for $129 and sells elsewhere in the $89-to-$99 range.This is one item of many available as part of eBay’s Labor Day Sale (which, at this writing, doesn’t specifically mention Labor Day, but that’s how it was pitched to us). $59 at eBay Tags Angela Lang/CNET Share your voice HP Laptop 15t Value: $520 (save $780) $60 at Best Buy Sarah Tew/CNET 16 Photoscenter_img $999 Read the AirPods review Chris Monroe/CNET Read Lenovo Smart Clock review Sci-Tech Lenovo 130-15AST 15.6-inch laptop: $210 (save $90) Will do Starship presentation a few weeks after Hopper hovers, so prob late July. If that timing works, free LJ chips for all present!— Elon Musk (@elonmusk) July 7, 2019 An Echo Dot makes a fine match for any Fire edition TV, because you can use the latter to say things like, “Alexa, turn on the TV.” Right now, the 24-inch Insignia Fire TV Edition starts at just $100, while the 32-inch Toshiba Fire TV Editions is on sale for $130. Just add any Fire TV Edition to your cart, then add a third-gen Echo Dot, and presto: The latter is free. Share your voice Sarah Tew/CNET $261 at Daily Steals via Google Express $155 at Google Express Read Google Home Hub review See It Sprint Though not technically a Labor Day sale, it’s happening during Labor Day sale season — and it’s too good not to share. Nationwide Distributors, via Google Express, has just about the best AirPods deal we’ve seen (when you apply promo code ZBEDWZ at checkout). This is for the second-gen AirPods with the wireless charging case. Can’t imagine these will last long at this price, so if you’re interested, act fast. The problem with most entry-level laptops: They come with mechanical hard drives. That makes for a mighty slow Windows experience. This Lenovo model features a 128GB solid-state drive, so it should be pretty quick to boot and load software, even with its basic processor. Plus, it has a DVD-burner! That’s not something you see in many modern laptops, especially at this price. Comments See it $520 at HP Use promo code 19LABOR10 to get an unusually good deal on JBL’s interesting hybrid product — not quite headphones, and not quite a traditional speaker, but something you wear like neckphones to listen to music on the go. Elon Musk Space SpaceX,I’m shocked — shocked! — to learn that stores are turning Labor Day into an excuse to sell stuff. Wait — no, I’m not. As much as I respect the original intent of the holiday (which became official back in 1894), to most of us, it’s just a bonus day off — one that’s blissfully tacked onto a weekend. So, yeah, stores; go ahead, run your sales. I’m listening. Perhaps unsurprisingly, Labor Day doesn’t bring out bargains to compete with the likes of Black Friday (which will be here before you know it), but there are definitely some sales worth your time.For example:We’ve rounded up the best Labor Day mattress deals.We’ve also gathered the best Labor Day laptop deals at Best Buy.The 2019 Vizio P Series Quantum is back under $999.Be sure to check out Amazon’s roughly three dozen Labor Day deals on TVs and audio. Google Express is having a big sale as well, one that includes deals on game consoles, AirPods, iPhones, laptops and more.Below I’ve rounded up a handful of individual items I consider to be the cream of the crop, followed by a handy reference guide to other Labor Day sales. Keep in mind, of course, that products may sell out at any time, even if the sale itself is still running. Note that CNET may get a share of revenue from the sale of the products featured on this page. Best laptops for college students: We’ve got an affordable laptop for every student. Best live TV streaming services: Ditch your cable company but keep the live channels and DVR. $6 at Tidal See It Recently updated to include digital-photo-frame capabilities, the Lenovo Smart Clock brings Google Assistant goodness to your nightstand. It’s a little smaller than the Amazon Echo Show 5, but also a full $30 less (and tied with Prime Day pricing) during this Best Buy Labor Day sale. $299 at Amazon Turo is kind of like Uber meets Airbnb: You borrow someone’s car, but you do all the driving. I’ve used it many times and found it a great alternative to traditional car-rental services — in part because you get to choose exactly the vehicle you want (not just, say, “midsize”) and in part because you can often do pickup and dropoff right outside baggage claim.Between now and Sept. 1, the first 300 people to check out can get $30 off any Turo rental with promo code LDW30. Other Labor Day sales you should check out Best Buy: In addition to some pretty solid MacBook deals that have been running for about a week already, Best Buy is offering up to 40% off major appliances like washers, dryers and stoves. There are also gift cards available with the purchase of select appliances. See it at Best BuyDell: Through Aug. 28, Dell is offering an extra 12% off various laptops, desktops and electronics. And check back starting Aug. 29 for a big batch of Labor Day doorbusters. See it at DellGlassesUSA: Aug. 29 – Sept. 3 only, you can save 65% on all frames with promo code labor65. See it at GlassesUSALenovo: The tech company is offering a large assortment of deals and doorbusters through Labor Day, with the promise of up to 56% off certain items — including, at this writing, the IdeaPad 730S laptop for $700 (save $300).See it at LenovoLensabl: Want to keep the frames you already love and paid for? Lensabl lets you mail them in for new lenses, based on your prescription. From now through Sept. 2 only, you can save 20% on the blue light-blocking lens option with promo code BLOCKBLUE. See it at LensablSears: Between now and Sept. 7, you can save up to 40% on appliances (plus an additional 10% if you shop online), up to 60% on mattresses, up to 50% on Craftsman products and more. The store is also offering some fairly hefty cashback bonuses. See it at SearsNote: This post was published previously and is continuously updated with new information.CNET’s Cheapskate scours the web for great deals on tech products and much more. For the latest deals and updates, follow the Cheapskate on Facebook and Twitter. Questions about the Cheapskate blog? Find the answers on our FAQ page, and find more great buys on the CNET Deals page. $999 Sarah Tew/CNET Review • iPhone XS review, updated: A few luxury upgrades over the XR $210 at Best Buy Free Echo Dot with an Insignia or Toshiba TV (save $50) DJI’s answer to GoPro’s action cameras is rugged little model that’s shockproof, dustproof and waterproof down to 11 meters. It normally runs $350, but this deal drops it to $261 when you apply promo code 19LABOR10 at checkout. Boost Mobile SpaceX has been building a Starhopper prototype of its Starship vehicle at the company’s facility in south Texas. Starship is the vehicle Musk and SpaceX hope to use for a highly publicized trip around the moon in a few years, as well as for future trips to Mars and perhaps even very quick international flights via space. So far, testing of Starhopper has been limited to hold-down firings of its single Raptor engine. Plans for it to actually lift off the ground and at least hover (or “hop”) before landing have been delayed in recent weeks. Musk also said Sunday that Starhopper is “almost ready to hover” after a vibration problem with the Raptor engine was resolved. The Tesla Motors and SpaceX CEO has conceded in the past that he isn’t always great about sticking to his own timelines. Starship, however, seems like it could be progressing steadily toward a first crewed trip to Mars in 2024 as hoped. Of course, it still has to get off the ground first.  Tidal 3-month family subscription: $5.99 (save $54) Tags Amazonlast_img read more

Modi assures Bangladesh of resolving Rohingya crisis

first_imgForeign minister AK Abdul Momen meets Indian prime minister Narendra Modi in New Delhi Thursday morning. Photo: BSSIndian prime minister Narendra Modi on Thursday assured New Delhi’s cooperation in resolving the longstanding Rohingya crisis in Bangladesh.His assurance came when visiting Bangladesh foreign minister AK Abdul Momen sought India’s support for early repatriation of Rohingya people to Myanmar’s Rakhine state as he met the Indian premier in New Delhi Thursday morning.As Momen thanked prime minister Modi for India’s humanitarian assistance to Rohingyas, the premier said India is always with Bangladesh and will remain beside it, a press release issued by Bangladesh mission in New Delhi said.During the meeting, the Indian prime minister mentioned that the partnership between Bangladesh and India is flourishing under the visionary leadership of prime minister Sheikh Hasina.He reaffirmed India’s sincere commitment to Bangladesh’s prosperity and development and viewed that Bangladesh-India relations are a model between the two neighbouring countries which need to be showcased for wider audience around the world.The foreign minister expressed his satisfaction on the excellent bilateral relations that exist between the two countries which had grown and prospered, especially with the statesmanship of prime minister Sheikh Hasina and prime minister Modi.He stressed that Bangladesh would continue her resolve in further strengthening and deepening her relations with India in the coming days.Momen recalled that the two countries amicably resolved the longstanding problems, which is much appreciated by the respective peoples.He also thanked prime minister Modi for extending congratulations upon the victory of Awami League in the parliamentary elections, held in December 2018 as the first foreign leader.The foreign minister mentioned the remarkable progress Bangladesh has achieved during the last few years in the socio-economic sectors under the Awami League government led by prime minister Sheikh Hasina.He also elaborated on the road map of prime minister Sheikh Hasina to realize the dream of Bangabandhu Sheikh Mujibur Rahman to build Bangladesh as Sonar Bangla.Later, foreign minister Momen called on the former Indian prime minister Manmohan Singh and deputy leader of opposition in the Rajya Sabha Anand Sharma.He conveyed greetings of prime minister Sheikh Hasina to Manmohan Singh.They expressed satisfaction at the excellent state of bilateral relations between Bangladesh and India.Manmohan Singh conveyed congratulations to prime minister Sheikh Hasina for being elected as the prime minister for the third time. He noted that early repatriation of Rohingyas is a priority and assured that they will be supporting the government of India in any initiative to expedite repatriation of Rohingyas to Rakhine state.He hoped that both countries would be able to resolve the remaining outstanding issues between the two countries including the Teesta water sharing soon.Momen is visiting New Delhi on his maiden official tour abroad as the foreign minister of Bangladesh to attend the 5th meeting of India-Bangladesh Joint Consultative Commission Friday.The meeting would be co-chaired by the foreign/external affairs ministers of Bangladesh and India.After the JCC meeting both sides are expected to sign few MoUs. Foreign minister is expected to return to Dhaka on 9 February 2019, the release added.last_img read more

Faruq spreads literacy in remote villages

first_imgFaruq Hossain. Photo: Prothom Alo“I won’t spend excesively or buy expensive clothes. I’ll spend one fourth of my salary on education for children of poor families.” Armed with this oath, 32-year-old Faruq Hossain has been working in a remote area of Dinajpur sadar upazila for the last 10 years.Faruq is from Malipukur village in Auliapur union of Dinajpur sadar upazila. He is an assistant to a truck driver of Bangladesh Agricultural Development Corporation (BADC).He spends 25 per cent of his monthly salary of Tk 14,900 for the education of poor people’s children. He takes care of his four-member family, comprising himself, his mother Sanwara Begum, wife Sabera Akhter and two-and-a-half-year-old son Sabbir Hossain with rest of the money.Faruq distributes education material among the students every Friday and Saturday. He also has set up a centre for educating adults at his house.In recognition of his initiatives, Faruq was awarded by the prime minister Sheikh Hasina on 13 March this year.The Malipukur village is 4.5 kilometres away off Dinajpur sadar upazila. On 10 February, the Prothom Alo correspondents visited Faruq’s home. He lives in a dilapidated mud-house. Relatives said Faruq’s father Mahbub Hossain passed away in 2006. He was a labourer at BADC. Faruq also joined as a labourer at BADC in 2002.All the labourers used to draw their wages with thumbprints as they were not literate and could not sign their names. Faruq studied up to the eighth grade. He started educating his fellow workers so that everyone would be able to sign their names to draw their wages.Saving his pocket-money along with some taken from his father, Faruq bought 200 taka worth of pens and papers for the labourers. Gradually he imparted basic literacy to all of them. Delighted, a driver Naresh Chandra taught Faruq how to drive. Faruq then joined as a temporary driver at the office of the deputy director of BADC in Rajshahi in 2007. Later on 16 July that year, he was appointed as an assistant to the truck driver and transferred to Rangpur BADC office. Since then, he is working as a driver of BADC joint director (seed processing centre) AFM Saiful Islam.Unlike others, Faruq did not stop there. “I had a dream to be self-sufficient after completing my studies. But poverty cut my dreams short when I was an eighth grader at Cheradangi High School. That’s why I decided to help those who could not continue studying due to poverty,” said Faruq to Prothom Alo.Faruq said the studies of Nur Islam from Kashimpur Mahanpara village came to a halt due to lack of education material and proper clothes in July 2008. He went to Nur Islam’s home and gave his mother 3000 taka. Nur Islam is now a student at Dinajpur Government College.In December that year, Faruq held a meeting with the seniors of the village. He told them he would not eat paan (betel leaf), smole cigarettes or buy expensive clothes. Instead he will help students from poor families. In 2009, he bought education material and clothes for 20 students with 25 per cent of his salary and admitted them to school. As of now, Faruq said, he has helped almost 2,000 students of the union.Ninth grader Zahid Hossain, eighth grader Amena and seventh grader Abdus Sattar at Cheradangi High School are some of the students from poor families who received Faruq’s help.When Sima Akhter from Malipukur village was a fifth grader, her father Samirul Islam went missing. Her mother arranged her marriage after three months. But the marriage was halted when Faruq pledged to take care of her education. Sima is now an eighth grader at Sikderganj Girls High School.“Faruq uncle has given me a new life. I want to be a physician,” Sima told Prothom Alo.Another student of Sikderganj Girls High School, Tanjila Khatun, showing her schoolbag, said, “Faruq uncle has bought this for me. He also has given me money for private tuition.”The school’s head teacher of Zakir Hossain said, “Faruq has been showing us the potential of dropout students. He also works to raise awareness to keep the village free of drugs and to ensure road safety. He also plants trees to keep the environment cool.”Kashimpur Government Primary School’s head teacher Jalal Uddin said, “Faruq distributes pens, pencils, papers and other stationery to students of different schools twice in a month. He also goes to the house to inquire if any student remains absent at school. This is why cent per cent children of Kashimpur attend school.”Faruq uses his bicycle to go from one school to another. There are several awareness raising stickers stuck to his bicycle against taking drugs, for road safety and against child marriage, etc.Mousumi Khatun was married off when she was an eighth grader. Her in-laws were against her studies. Faruq persuaded her in-laws to allow her to study and took charge of Mousumi’s education.“The dreams of many girls like me are being fulfilled thanks to Faruq uncle. Now I’m studying in college,” Mousumi said.Auliapur union parishad chairman Abdur Razzak considers Faruq a social welfare activist. He was recognised as such on 13 March this year when the prime minister Sheikh Hasina handed over a medal at a programme organised marking National Primary Education Week at Bangabandhu International Conference Centre in Dhaka.Adult education centre at homeFaruq has opened an adult education centre at home where his wife Sabera Akhter teaches adults of the village.Faruq married Sabera of Boaldhar village in Baliadangi of Thakurgaon in 2010. She was a ninth grader then.“I resumed studies upon Faruq’s insistence. In 2011, I took up diploma in agriculture at KBM College in Dinajpur. Now I’m a bachelor degree student at Open University,” Sabera told Prothom Alo.An older woman Shirin Akhter said there was no one in the village who cannot write his/her name.“Maybe Faruq has not given us material wealth, but we’re living with honour for his efforts,” Sabera said.Faruq said he does not work for awards. “I started working so that no one of my area lives in the darkness of illiteracy. This will continue until the dropout rate comes down to zero.”*The report appeared in the print edition of Prothom Alo and has been rewritten in English by Shameem Rezalast_img read more